Serum amyloid A concentration as an inflammatory marker in endotoxemic model calves

Authors

  • M. Otsuka The School of Veterinary Medicine, Rakuno Gakuen University, 582 Midorimachi, Bunkyoudai, Ebetsu, Hokkaido 069-8501 Japan
  • Y. Nishi The School of Veterinary Medicine, Rakuno Gakuen University, 582 Midorimachi, Bunkyoudai, Ebetsu, Hokkaido 069-8501 Japan
  • M. Tsuchiya Microbial Solutions, Charles River, 1023 Wappoo Road, Suite 43B Charleston, SC 29407
  • K. Suzuki The School of Veterinary Medicine, Rakuno Gakuen University, 582 Midorimachi, Bunkyoudai, Ebetsu, Hokkaido 069-8501 Japan

DOI:

https://doi.org/10.21423/aabppro20197288

Keywords:

Serum amyloid A, inflammatory disease, endotoxemia

Abstract

Serum amyloid A (SAA) is an acute phase protein that increases in concentration in the serum in the early stages of inflammation. SAA is used to diagnose inflammatory diseases in humans, cats, and horses. Such an inflammatory marker to diagnose inflammatory diseases needs to be investigated in cattle. Furthermore, the relationship between systemic inflammation and serum SAA concentrations needs to be examined in order to improve food animal health care. However, no studies have been reported on the sequential change in SAA in cattle with endotoxemia. Therefore, the aim of the present study was to examine serum SAA concentrations in cattle with systemic inflammation caused by endotoxin.

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Published

2019-09-12

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