Serum antibody response in calves receiving modified live and/or inactivated vaccines containing bovine herpesvirus-1, bovine viral diarrhea virus, parainfluenza-3 virus, and bovine respiratory syncytial virus immunogens

Authors

  • Robert W. Fulton Department of Infectious Diseases and Physiology, College of Veterinary Medicine, and Department of Statistics, Oklahoma State University, Stillwater, OK 74078
  • Lurinda J. Burge Department of Infectious Diseases and Physiology, College of Veterinary Medicine, and Department of Statistics, Oklahoma State University, Stillwater, OK 74078
  • J. M. d'Offay Department of Infectious Diseases and Physiology, College of Veterinary Medicine, and Department of Statistics, Oklahoma State University, Stillwater, OK 74078
  • Mark E. Payton Department of Infectious Diseases and Physiology, College of Veterinary Medicine, and Department of Statistics, Oklahoma State University, Stillwater, OK 74078

DOI:

https://doi.org/10.21423/bovine-vol1997no31.2p90-96

Keywords:

antibodies, antibody formation, antigens, calves, immune response, immunization, inactivated vaccines, live vaccines, mucosal disease, serology, young animals

Abstract

Serum antibody responses to bovine herpesvirus-1 (BHV-1) bovine viral diarrhea virus (BVDV), parainfluenza-3 virus (PI-3V), and bovine respiratory syncytial virus (BRSV) by calves receiving viral vaccines were evaluated. Calves were vaccinated at day 0 with one of four commercial vaccines containing BHV-1, BVDV, PI-3V, and BRSV immunogens. Selected vaccines were given a second time at day 28. Calves were revaccinated at day 140 with the respective vaccine given at day 0. The vaccines contained modified live virus (MLV) and/ or inactivated components. Serums were collected at day 0 and at various intervals through day 196, and assayed for viral neutralizing antibodies. Between various vaccine groups there were differences in onset and duration of serum antibodies to each immunogen postvaccination. Anamnestic responses after day 140 revaccination to some but not all viruses were sometimes dependent on the type vaccine and level of antibodies at revaccination.

Cover image of Volume 31.2 of the Bovine Practitioner: a photo of the Montréal waterfront in mid-afternoon

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Published

1997-05-01

How to Cite

Fulton, R. W., Burge, L. J., d’Offay, J. M., & Payton, M. E. (1997). Serum antibody response in calves receiving modified live and/or inactivated vaccines containing bovine herpesvirus-1, bovine viral diarrhea virus, parainfluenza-3 virus, and bovine respiratory syncytial virus immunogens. The Bovine Practitioner, 1997(31.2), 90–96. https://doi.org/10.21423/bovine-vol1997no31.2p90-96

Issue

No. 31.2 (1997 May)

Section

Articles

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