Experimental oxytetracycline toxicity in feedlot heifers

Authors

  • D. D. Griffin Department of Large Animal Clinic, School of Veterinary Medicine, Purdue University, West Lafayette, Indiana, 47906
  • R. L. Morter Department of Large Animal Clinic, School of Veterinary Medicine, Purdue University, West Lafayette, Indiana, 47906
  • H. E. Amstutz Department of Large Animal Clinic, School of Veterinary Medicine, Purdue University, West Lafayette, Indiana, 47906
  • G. D. Boon Department of Veterinary Microbiology, Pathology and Public Health, School of Veterinary Medicine, Purdue University, West Lafayette, Indiana, 47906

DOI:

https://doi.org/10.21423/bovine-vol1979no14p37-41

Keywords:

Adverse effects, animal husbandry, Antibiotics, Disease prevention, Drug therapy, drug toxicity, oxytetracycline, respiratory diseases, Tetracyclines, toxicity

Abstract

Oxytetracycline had been widely used at 11 mg/kg for the treatment of respiratory disease in feedlot cattle. The increased prevalence of resistant strains of Pasteurella sp. has resulted in recommendations for increasing the dose to 33 mg/kg or as much as 55 mg/kg. The 33 mg/kg dose given to seven normal feedlot heifers i/v for three successive days produced signs of nephrotoxicity but no deaths.

Cover image of the 14th Volume of the Bovine Practitioner: a photo of the San Antonio riverwalk during the holidays: a tree-lined waterway lined with twinkling lights and an elegant bridge covered in ivy.

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Published

1979-11-01

How to Cite

Griffin, D. D., Morter, R. L., Amstutz, H. E., & Boon, G. D. (1979). Experimental oxytetracycline toxicity in feedlot heifers. The Bovine Practitioner, 1979(14), 37–41. https://doi.org/10.21423/bovine-vol1979no14p37-41

Issue

No. 14 (1979 November)

Section

Articles

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